SPSS 22.0 software (Chicago, USA) was employed to analyze the data. All representative data were shown as the mean ± standard deviation (SD) [2325]. We carried out the Students' t-test and one-way ANOVA to separately determine the difference existing in two groups and multiple groups. p value < 0.05 was denoted as a significantly statistical difference [2628]. All experiments were performed in three independent times in replicates at one time.

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