Baseline characteristics are presented as median [range] or counts (percentages). Outcomes are presented for the total cohort and separately for the total pancreatectomy and Whipple/PPPD subgroups. Patients undergoing a total pancreatectomy or completion pancreatectomy were analyzed as total pancreatectomy, and patients undergoing a Whipple/PPPD with or without distal pancreatectomy were studied as Whipple/PPPD. Additionally, the Whipple/PPPD plus distal pancreatectomy subgroup was separately analyzed. Differences in patient, disease, surgical, and intraoperative characteristics were compared between patients with and without a severe complication using Chi square, Fisher’s exact, or Mann–Whitney U tests. Univariable logistic regression was performed to identify factors associated with a severe complication. Variables were selected based on clinical reasoning and included age at surgery (years), sex (female vs. male), center volume (high vs. low), ASA score (1 and 2 vs. 3), tumor size (mm), pNET size ≥ 2 cm (present vs. absent), type of resection (Whipple/PPPD vs. total pancreatectomy), period of surgery (2003–2010 vs. 2011–2017), operative time (minutes), and intraoperative blood loss (mL). Odds ratios (OR) with corresponding 95% confidence intervals (CIs) were calculated. Considering the low number of included patients and low absolute number of patients with a severe complication, multivariable analysis was deemed inappropriate. No missing data were observed for variables assessed by logistic regression. Two-tailed p-values < 0.05 were considered statistically significant. Analyses were performed using SPSS version 25.0 (IBM Corporation, Armonk, NY, USA) and R version 3.5.1 (The R Foundation for Statistical Computing, Vienna, Austria).

Note: The content above has been extracted from a research article, so it may not display correctly.



Q&A
Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.



We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.