2.14. In Vitro MX Release Study
This protocol is extracted from research article:
Lyophilized Composite Loaded with Meloxicam-Peppermint oil Nanoemulsion for Periodontal Pain
Polymers (Basel), Jul 14, 2021; DOI: 10.3390/polym13142317

The release of MX from MX-SNELCs was assessed in triplicate by employing a paddle-type USP dissolution test apparatus with simulated saliva fluid (500 mL) at pH 6.8 and 37 ± 0.5 °C. The test was carried out at 50 rpm, and 5 mL samples were withdrawn, filtered through a 0.45-μm filter, then quantified for MX. The medium was maintained at a fixed volume by introducing the same volume of fresh medium to compensate for the loss of volume during sampling at each time point.

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