Data using cell cultures were analyzed using an unpaired t-test when comparing 2 groups or a one-way ANOVA when comparing multiple groups. Data from patient samples were analyzed using Wilcoxon matched-pairs signed rank test. The correlation between two factors was evaluated using the Spearman’s correlation. All statistical evaluations were carried out using GraphPad Prism software. Results were considered statistically significant when p < 0.05.

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