After mice were sacrificed, the skin was removed, sliced, embedded in paraffin wax (Sigma Aldrich, St. Louis, MO, USA), and stained with haematoxylin and eosin (Sigma Aldrich) for further microscopic examination. The digital scanner (Pannoramic MIDI, 3DHistech, Budapest, Hungary) was used to scan photomicrographs (20×).

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