All patients with more than 1 year follow up in outpatient visits were enrolled. Patients requiring medium to high dose ICS and LABA or leukotriene modifier/theophylline for the previous year, or those treated with systemic corticosteroids for more than half a year to prevent from becoming uncontrolled, or those remaining uncontrolled despite this therapy were further included in the study as severe asthma patients. Patients fulfilling at least one of the following criteria are defined as uncontrolled asthma: (1) having ACQ score > 1.5 or ACT score < 19, (2) treated with two or more bursts of systemic corticosteroids, (3) having at least one hospitalization, ICU stay or mechanical ventilation in the previous year, (4) having FEV1 < 80% predicted after appropriate bronchodilator withheld and with reduced FEV1/FVC.

Note: The content above has been extracted from a research article, so it may not display correctly.



Q&A
Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.



We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.