Data were expressed as mean values ± SDs. Descriptive statistical analyses were conducted using the Analyse-it software package (Analyse-it, UK). A Shapiro–Wilk test showed that the data groups had normal distributions. A one-sided Student’s t-test served to assess the level of statistical significance between differences of data means from HDFs cultured on 3D-SFnws versus HDFs cultured on polystyrene. A one-way analysis of variance with a post hoc Tukey’s test served for multiple comparisons of the results from endothelial tube formation assays. The statistical significance level was set at p < 0.05.

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