Carboxymethylcellulose sodium (Mw = 90,000), adipic dihydrazide, sodium periodate (NaIO4, Analytical Reagent, AR), N-(3-dimethylaminopropyl)-N-ethylcarbodiimide (EDC) and 1-Hydroxybenzotriazole hydrate (HOBt) were purchased from Macklin Biochemical Co. Ltd. (Shanghai, China). β-Cyclodextrin (Mw = 1135), DMSO (AR) were obtained from Kermel Chemical Reagent Co. Ltd. (Tianjin, China). Cyclohexane (AR), Methanol (AR) were purchased from Fuyu Fine Chemical Co., Ltd. (Tianjin, China) and used as received. Ginsenoside CK (purity > 95%) was provided by the Biomedical Research Institute of Northwest University (HPLC ≥ 95%, Xi’an, China). RPMI1640 medium and penicillin/streptomycin were purchased from GIBCO (Grand Island, NY, USA). Hoechst 33342 was obtained from Beyotime Biotechnology (Shanghai, China). MTT, 4′,6-diamidino-2-phenylindole (DAPI) and Fluorescein isothiocyanate (FITC) were purchased from Beijing Solarbio Science & Technology Co., Ltd. (Beijing, China).

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