We collected data from patients with confirmed COVID-19 hospitalized in our unit from March 2020 through November 2020. We included patients aged >18 years, with a positive RT-PCR for SARS-CoV-2, supplemental oxygen requirement, and abnormal chest imaging that received either baricitinib plus dexamethasone or dexamethasone monotherapy. Severe COVID-19 pneumonia was defined as dyspnea, with at least one of the following: a respiratory rate of 30 or more breaths per minute, a blood oxygen saturation of 93% or less, a ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen (PaO2/FiO2) of less than 300 mm Hg, or pulmonary infiltrates in more than 50% of the lung fields.14

We excluded patients with a hospital stay less than 24 h, patients without oxygen requirement or patients that received any other therapies such as convalescent plasma, tocilizumab, remdesivir or methylprednisolone.

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