Seeds of Opuntia ficus-indica (L.) Mill. (OFI) were purchased from Al-Baha governorate, Saudi Arabia and was identified by Dr. Emad Al-Sharif (Plant Ecology, Dept. of Biology, Faculty of Science & Arts, Khulais, King Abdulaziz University, KSA). A sample was kept in the herbarium of Faculty of Pharmacy, King Abdulaziz University (OFI-1241). One kilogram of the seeds was extracted with hexane using Soxhlet apparatus as previously reported.17

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