The PCCI is an externally validated, long-term, other-cause mortality prediction tool for early-stage PCa modeled after the Charlson Comorbidity Index.24 It uses age and comorbidity at diagnosis to provide a weighted numerical score predicting long-term, other-cause mortality in men with PCa. The PCCI is calculated by adding 1 point for each 6 years older than 60 years and additional points for the number and type of comorbidities, as previously described.17 Prostate Cancer Comorbidity Index scores were grouped a priori into 4 categories (0-2, 3-6, 7-9, and ≥10) based on similar long-term mortality rates in a prior study of men with PCa in the VA Health System.17

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