Statistical analysis was carried out using GraphPad Prism 8 and R 3.6.3 ( The subgroups were divided based on the median value. Kaplan–Meier survival analysis was used to generate overall survival curves, and the log-rank test was used to calculate the significance. The nine gene score was evaluated using single-sample gene set enrichment analysis (ssGSEA). The “survival”, “ggplot2”, “corrplot”, “pheatmap”, “GSVA” and “limma” packages were built using R version 3.6.3. Differences with P < 0.05 were considered significant.

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