In GSE65904 and TCGA-SKCM, we investigated the correlation between CD8+ T cell-related genes and immune responses in melanoma, then drew the heat map. We selected several classic immune-related metagene sets, including major histocompatibility complex class I (MHC-1), major histocompatibility complex class II (MHC II), lymphocyte specific kinase (LCK), hematopoietic cell kinase (MCK), immunoglobulin G (IgG), signal transduction and activation transcription 1 (STAT1) and interferon (21).

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