PLTs, N@PLTs, and N+R@PLTs were resuspended in 1 ml of PBS at 1 × 1010 PLTs/ml, and N was suspended in 1 ml of PBS at 43.8 μg/ml (44.5 μM) in centrifuge tubes. Then, these tubes were irradiated upon 0.65 W/cm2 NIR laser for 10 min, and the thermal images were taken at 0, 1, 3, 5, 7, and 10 min.

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