Differentially expressed genes (DEGs) in matched groups were selected using the ‘limma’ package in R software with p‐values <0.05 and |Log2FC| >1. The bio‐information of DEGs was identified by Gene Ontology (GO) enrichment (biological processes [BP], cellular components [CC], and molecular functions [MF]) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses on the DAVID website (https://david.ncifcrf.gov/).

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