To examine the release behavior of Cur under H2O2 condition, 2.0 g Cur@CMCTS and Cur@CMCTS-Tk hydrogel were placed into 10 ml of cell lysate (RIPA lysis buffer) medium at 37°C. After 5 h, the releasing medium was added into 50 mM H2O2. At the appointed time, we took 8 ml of the mixed solution to investigate the release ratio via the ultraviolet spectrophotometer and replaced it with the same volume of fresh buffer solution instead.

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