Tube current reduction was performed virtually. For this purpose, a simulation algorithm based on raw imaging data was used, which allowed for generating MDCT scans with virtually lowered tube currents (25-27). The original scan with full dose without dose reduction or sparse sampling was defined as D100P100. The corresponding simulations had 50% (D50P100), 10% (D10P100), 5% (D5P100), and 3% (D3P100) of the original X-ray tube current.

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