The liver fat content was measured using proton magnetic resonance spectroscopy (MRI)26. Abdominal visceral fat and subcutaneous fat areas were measured by computed to mography (CT). Height and Body weight was measured in the morning before breakfast. Body mass index (BMI) was calculated as body weight in kilograms divided by the square of height in meters (kg/m2). All study outcomes were measured at baseline and 6- and 12-follow-up visits.

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