Experimental design and grouping
This protocol is extracted from research article:
BAPN-induced rodent model of aortic dissecting aneurysm and related complications
J Thorac Dis, Jun 1, 2021; DOI: 10.21037/jtd-21-605

Eighteen rats were randomly divided into 3 groups and were fed BAPN solution at a concentration of 0.2% (SD-0.2, n=6), 0.4% (SD-0.4, n=6), or 0.6% (SD-0.6, n=6). Forty C57BL6 mice were randomly divided into 4 groups and were fed 0.2% BAPN solution (C57-0.2, n=10), 0.4% BAPN solution (C57-0.4, n=10), 0.6% BAPN solution (C57-0.6, n=10), or distilled water (control, n=10). All animals had free access to food and water. Daily water drinking volume was recorded, together with body weight per week.

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