Statistical analyses were performed using SPSS statistical software (version 15.00) and the statistical package Jamovi (Version 1.2). Based on the status, the patients were assigned to either survival or non-survival group. Analysis were done taking the entire sample of men (n = 28) and women (n = 10). For categorical variables, absolute and relative frequencies by status were tabulated. The distribution of continuous variables was tested following the principal of the Shapiro-Wilk test (p < 0.05). Continuous variables between groups were compared using the student's t-test or the Mann-Whitney U test. Correlation analyses were performed by non-parametric Spearman test. The survival analysis was assessed using Kaplan-Meier survival function curve to test the statistical significance between the individuals who had a high level of cytokines and the subjects who had a low level of cytokines at 50% and 75% cutoff. A significance of 0.05 was considered with no correction for p-values.

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