Antibodies used were from Cell Signaling (Danvers, MA, USA) against DYRK1A, P107, P16, p-RB, RB, p-CycD1, CycD1, CycB1, p-CDK1, Ki67, GAPDH, anti-rabbit HRP-linked, anti-mouse HRP-linked; from Abcam (Cambridge, UK) against CDK1, p-CDK1, CDC23, LIN52; and from Santa Cruz Biotechnology (Dallas, TX, USA) against LIN37, DYRK1A, LIN9, P130.

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