The target genes related to CHB were gathered from followed three databases. The GeneCards database (https://www.genecards.org/), the DisGeNET database (https://www.disgenet.org/) and the NCBI gene database (https://www.ncbi.nlm.nih.gov/gene/). The search condition was using the keyword “Chronic Hepatitis B” and selecting the organisms “Homo sapiens” from the three platforms. The above gene ID was identified and standardized in the UniProt database (https://www.uniprot.org). We used Retrieve/ID mapping tool of UniProt to convert identifiers, which are of a different type to UniProt identifiers.

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