Further information and requests for resources and reagents should be directed to and will be fulfilled by Lead Contact, Felipe Cortés-Ledesma (fcortes@cnio.es).

All unique/stable reagents generated in this study are available from the Lead Contact with a completed Materials Transfer Agreement.

Data are available in the main text, supplementary materials and auxiliary files. The accession number for all the sequencing data generated in this manuscript is GEO: GSE141800.

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