In this meta-analysis, the clinical heterogeneity among study results was analyzed by Chi-squared (χ2) test, the test level was α = 0.1, and I2-test was used to measure the heterogeneity. Where results are homogeneous (P > 0.1, I2 < 50%), the fixed-effects model was used for meta-analysis. If heterogeneity existed among the study results (P ≤ 0.1, I2 ≥ 50%), the random-effects model was used for meta-analysis. The Z test was used for the combined effect value, and the test level was α = 0.05. To estimate the size of the comprehensive effect, sensitivity analysis was performed on the meta-analysis again after eliminating individual studies. Publication bias was visually judged by drawing funnel plots and quantitative detection by using the Egger regression method, and the test level was α = 0.05. Statistical analyses were performed using the Review Manager, version 5.3. There is currently no registered protocol for this meta-analysis.

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