The search was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We conducted a systematic electronic search of the Medline and Embase databases up to April 2020. Different combinations of keywords used for preliminary search were as follows: “neutrophil” or “neutrophils,” “lymphocyte” or “lymphocytes,” “platelet” or “platelets,” “monocyte” or “monocytes,” “osteosarcoma” or “Ewing sarcoma” or “chondrosarcoma” or “bone sarcoma,” and “prognostic” or “prognosis” or “outcome” or “survival.” As this was a meta-analytic study using data only from published studies, ethical approval was waived.

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