For the clonogenic assays, the studies have been independently repeated at least three times. Results are expressed as mean of surviving fraction (SF) ± SD. The results were analyzed by one-way ANOVA. For in vivo CDDP experimentation, tumor growth curve was analyzed using mixed linear modeling (MLM), performed with R statistics software. GraphPad Prism 7.04 software was used to perform statistical analyzes. Significance was defined at the level of p<0.05.

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