Simple randomization in a 1:1 ratio will be made in blocks of variable size according to a random numbers generated by Excel 2010 to divided the patients to treatment group (intracoronary injection of 2 mg Nicorandil) and control group (intracoronary injection of 2 mL Saline). The attending physician, patients, outcome evaluators, and statistical analysts will be blinded to the allocation. To maintain blinding, Nicorandil and Saline are in the same package and appearance.

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