2.6.1. Traditional meta-analysis

We will execute Rev Man 5.3 and STATA 14.2 software for traditional meta-analysis. For dichotomous data, we will calculate a summary estimate with 95% confidence interval (CI) odds ratio (OR) value; for continuous data, we will calculate a summary estimate of standardized mean difference (SMD) with 95% CI, and P < .05 is considered statistically significant. The heterogeneity among the included literature will be assessed using the Q test method and I2 statistic method. When the Q statistic corresponds to P ≤ .10 or I2 >50%, it indicates that there is heterogeneity among the included literature, and assess the effect size by the random effect; on the contrary, a fixed-effect model is used.

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