Stratified block randomization will be conducted by the Zhejiang Hospital of Traditional Chinese Medicine with their online central randomization system. The recruitment process will be overseen by a Clinical supervisor. Each patient will be given a unique ID through a web interface provided by Clinical Data Centre of Zhejiang Hospital of Traditional Chinese Medicine. Patients will be randomly allocated to the experimental group and the control group at a ratio of 1:1 according to the ID given by the central randomization system. Each trial drug will also be labeled with a unique number and dispatched with the online system at each visit. All experimental plaster and corresponding placebo plaster are consistent in appearance and taste. The grouping information of each participant will be concealed to all research personnel and data analyzers until the end of trial. Unblinding will be permitted when serious adverse events occur.

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