In order to achieve a consistency (at least 80%) of extracted items, the data extractors will extract data from a sample of eligible studies. Results of the pilot extraction will be discussed among review authors and extractors. Two independent reviewers will extract data with a predefined extraction template, which includes the following items: study characteristics such as the first author, publication year, study design, follow-up period; patient demographic details such as patients’ number, average age, and gender ratio. The outcomes include any rating scale describing stress, mood, and quality of life. The original authors will be contacted to request missing data where necessary. Extracted information will be cross-checked by 2 independent reviewers. Any disagreements will be discussed and resolved in discussion with a third reviewer.

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