2.2.2. Assessment periventricular echodensities (PVE) cerebral hemorrhages hydrocephaly
This protocol is extracted from research article:
Predicting the developmental outcomes of very premature infants via ultrasound classification
Medicine (Baltimore), Apr 16, 2021; DOI: 10.1097/MD.0000000000025421

PVE were defined and classified in reference to van Wezel–Meijler et al.[4] Cerebral hemorrhages were classified in accordance with the Papile standard.[5] Hydrocephaly grades were classified into 3 degrees on the basis of ventricular index and in accordance with Lara et al mild hydrocephaly- less than 13 mm; moderate hydrocephaly- 13 to 15 mm, and severe hydrocephaly- more than 15 mm.[5] Weekly and monthly ultrasonic reports of the infants were obtained for brain injury classification. Images of the first cUS, TEA-cUS, and last cUS were reviewed blindly by 2 doctors and classified to 3 degrees in accordance with PVE grade, hydrocephaly degree, cystic periventricular leukomalacias (c-PVL) and hemorrhage grade of the Papile standard.

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