2.2. Literature search strategy
This protocol is extracted from research article:
Evaluation of association between methylenetetrahydrofolate reductase and azoospermia
Medicine (Baltimore), Apr 16, 2021; DOI: 10.1097/MD.0000000000024523

Multiple electronic databases including MEDLINE, EMBASE, Cochrane library, and China journal full-text database were searched from January 2000 to September 2019 using combinations of the following key terms: MTHFR and azoospermia. The Mesh words included methylenetetrahydrofolate reductase (NADPH2), azoospermia, and nonobstructive. There was no language restriction. Title and abstract were initially reviewed and the references were also examined (G-XT and LJ). Two authors assessed possibly related articles independently complying inclusion criteria and exclusion criteria. If there is disagreement between 2 researchers, a third author will help to solve it.

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