Study physicians recorded anthropometric data including the body height and weight, waist circumference, hip circumference, and blood pressure before and 1 month, 2 months, 6 months, and 12 months after the therapy. Fasting venous blood samples were tested for FPG, haemoglobin A1C (HbA1c), fasting C-peptide (FCP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TGs), complete blood count, albumin, vitamin B12, folate, ferritin, and iron. Two-hour venous blood samples were tested for post-prandial plasma glucose (PPG) and post-prandial C-peptide (PCP). HbA1c was measured by automated liquid chromatography (VARIANT II Haemoglobin Testing System; Bio-Rad Laboratories, Hercules, CA). C-peptide (CP) was measured by a chemiluminescence method (ADVIA Centaur; Siemens, Munich, Germany). The percentage of excess body mass index (BMI) loss was defined as (100 × [baseline BMI − follow-up BMI]/[baseline BMI − 25]).

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