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The statistical analyses were performed using Statistica 12 package (StatSoft Inc). Results are reported as mean (SD) for continuous variables and n (%) for categorical variables. The t-test and ANOVA were used to compare the means of two groups (t-test) and three or more groups (ANOVA). Categorical variables were compared with chi square exact test. A logistic regression was used to predict the factors independently associated with ILD. A P value < 0.05 was considered significant.

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