The IDQoL is a validated questionnaire [5,27] that consists of 10 items regarding physical symptoms, disturbance of normal activities and sleep, and problems with bathing and dressing. Each item was scored 0–3 with a maximum score of 30, where higher scores represent a poorer quality of life [27], however, there are not validated score bands. An additional question was scored separately regarding the severity of dermatitis from 0 = ‘None’ to 4 = ‘Extremely severe’ as perceived by the caretaker.

Both the POEM and IDQoL are recommended as core instruments for AD research by the Harmonising Outcome Measures for Eczema international working group [28].

The DFI is a 10-item questionnaire, validated for use in families of children aged 6 months to 10 years old, that measures the impact of the child’s AD on the family unit over the past 7 days [29]. The DFI correlates well with the IDQoL [29,30]. Each item was scored from 0–3 for a maximum score of 30. Higher scores represent a greater impairment of the family as a result of AD. No validated score-banding system exists for the DFI.

All questionnaires were translated from English to Bangla by study physicians, pilot tested in the community, and adjusted after discussions with CHWs per ISAAC Phase 3 Manual recommendations [31]. Question 6 and question 4 in the IDQoL and DFI, respectively, were modified by removing the example of swimming as it was not culturally relevant. Question 5 in the DFI was modified from asking about “time spent on shopping for the family” to “time spent going to the market.”

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