# Also in the Article

Analysis
This protocol is extracted from research article:
Vaccination coverage estimation in Mexico in children under five years old: Trends and associated factors
PLoS One, Apr 16, 2021;

Procedure

In order to evaluate the groups’ homogeneity with and without VC in the first stage, a general description from the variable of interest in the surveys was carried out and they were compared using the Pearson’s Chi2 test, adjusting for the surveys´ design.

The missing information was imputed as described above. The probability of applying the 22 doses and two CBS ($Y^i$) was estimated to report the estimated vaccination coverage. Logistic regression models adjusted by the covariates described above and survey year were specified for the vaccination coverage purpose. Additionally, two interaction terms were included: caretaker’s sex and age and the survey year with the state. The analysis was adjusted by each year survey design and imputed information. Estimated coverages according to dose and CBS by age group, and the survey year were reported.

Aiming to identify determinants of the incomplete basic vaccination scheme from the two age groups (6–11 months and 12–23 months), the odds ratios were estimated with their respective confidence intervals for the variables: rurality, age, schooling, health insurance, and the caretaker indigenous condition. These estimates are reported globally, meaning the five surveys were included.

The models´ descriptive, imputation, and analysis were carried out with the statistical package STATA version 15 [34], while for the validation tests the R version 3.6.2 was used [35]. The confidence level and significance level were 95% and 0.05, respectively.

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