155 patients admitted to the ICU of the Medical Department III at the RWTH Aachen University Hospital between 2006 and 2015 were enrolled in our observational cohort study (see Table 1 for detailed patients´ characteristics). Only patients with an age of ≥18 years, an expected ICU stay of >72h and who received an CT-scan at ICU admission were included in our study. Written informed consent was obtained from all patients or authorized relatives / legal guardians in the case of unconsciousness. The study and specifically the consenting procedure were approved by the local ethics committee (EK 150/06) of the RWTH Aachen University Hospital, Germany, and conducted according to the ethical standards laid down in the Declaration of Helsinki. Patients´ follow-up and analysis of long-term mortality was performed up to two years after study inclusion.

For quantitative variables, median and range (in parenthesis) are given. Abbreviations are: BMI, body mass index; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, sequential organ failure assessment; SAPS-II, simplified acute physiology score; ICU, intensive care unit.

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