The RPPA data (level 4) of adult ACC were obtained from The Cancer Proteome Atlas (TCPA). The gene expression profiles and clinical information of patients with ACC were downloaded from The Cancer Genome Atlas (TCGA). Preprocessing and normalization of the raw biological data were performed using R software to remove noise and ensure the integrity of the data. By matching the sample IDs, we obtained 46 ACC cases with full data for clinical information, protein abundance and gene expression. We also obtained 76 ACC cases from TCGA (Table 1) and 22 ACC cases from GSE10927 18 (Table 2) in NCBI’s GEO database with full data for clinical information and gene expression. All the cases were patients over 18 years old.

Clinicopathological characteristics 76 adult ACC patients (TCGA cohort)

Clinicopathological characteristics of 22 adult ACC patients (GSE10927 cohort)

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