LX‐2 cells were seeded in 96‐well plates with DMEM which included 10% FBS for 24 hours. Then, the cells were exposed to different concentration of lenvatinib (0‐400 nmol/L) for 24 hours. The Premix WST‐1 Cell Proliferation Assay system (Takara Bio) was used to assess cell viability according to the manufacturer's protocol.

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