Any patient with an acute health issue who has sought medical advice/care from a PIONEER data partner. Any and all acute episodes can be included with no restriction on disease, condition or age. Patient data within PIONEER is collected as part of routine care. Longitudinal data will be eligible if it relates to, leads to or stems from an acute care contact. Patients will not need to specifically consent to their health data being used within PIONEER, but patients will not be included if they have chosen to opt out of the use or disclosure of their data for research and planning via the NHS National Data Opt-Out11 or if they have opted out of PIONEER specifically (see ethical considerations).

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