Data are presented as medians and their 25th–75th percentile IQR or counts and percentages. Comparisons between independent groups were made using the Mann-Whitney U test for continuous outcomes and the χ2 test (or Fisher’s exact test when appropriate) for quantitative data. Bonferroni correction was applied to correct for multiple testing, when appropriate. All tests were two-sided and p values <0.05 were considered statistically significant. Statistical analyses were performed with the software JMP13 (SAS Institute, Cary, NC, USA).

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