To analyse the significant change in cluster peak scores stimulated by CRP, we used paired Student’s t test. Fisher’s exact test is used to calculate p to test the significance of associations between gene sets. The remaining data in this study were assessed using unpaired Student’s t tests. The levels of significance were indicated as follows: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.

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