An Annexin V-fluorescein isothiocyanate/propidium iodide (FITC/PI) apoptosis detection kit was purchased from Multisciences (Lianke) Biotechnology (Hangzhou, China). Cell Counting Kit (CCK)8 detection kit and an enhanced chemiluminescence detection (ECL) kit were obtained from Beijing 4A Biotech (Beijing, China). TRIzol® Plus RNA Purification kit and MultiScribe RT kit were purchased from Invitrogen (Carlsbad, CA, USA). A SYBR Green RT-PCR kit (QPK-201) was from Toyobo (Tokyo, Japan). The primers used in the real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR) were provided by Shengon Biotech (Shanghai, China).

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