2.7.3. Specific Effects: Gastrointestinal Symptoms and Autonomic Nerve Function
This protocol is extracted from research article:
The Specific and Nonspecific Effects of Tai Chi and Its Possible Central Responses: A Protocol of Neuroimaging Study
Evid Based Complement Alternat Med, Feb 19, 2021; DOI: 10.1155/2021/8883460

To evaluate the changes of the gastrointestinal symptoms and QOL of participants, we performed the following measurements at the baseline, the median of intervention, and the end of intervention: CCS [21], patient assessment of constipation symptoms (PAC-SYM) [22], patient assessment of constipation QOL questionnaire (PAC-QOL) [23], RPE [24], and MOS 36-item short-form health survey (SF-36) [25]. Also, the evaluation of constipation diary, including CSBMs per week, the fecal character, and the difficulty degree of defecation, will be measured once a week for 10 times.

To evaluate the autonomic nervous function, we selected the heart rate variability (HRV). All participants will be assessed during the 24-h HRV at the baseline and the end of the intervention. The metrics of HRV include standard deviation of NN intervals (SDNN), standard deviation of sequential 5-min RR interval means (SDANN), and root mean square successive difference (RMSSD). The device used is a dynamic electrocardiogram (ct-086S; BENE WARE, Hangzhou, China).

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