As we reported previously [9], 11,267 patients (4830 females, 6437 males) from Southwest China participated in this research, which lasted from January 2010 to November 2014. They were patients ranging in age from 22 to 92 years (63.4 ± 13.8 years), who were admitted to the 3 southwestern hospitals to undergo CAG. These patients exhibited chest pains, shortness of breath, palpitations, and arrhythmias and were suspected to have CAD. The baseline clinical characteristics of all these patients are shown in Table 1 [9]. The study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki as reflected in an a priori approval by the institution's human research committee. Also, all patients have given their informed consent prior to their inclusion in the study.

Demographic characteristics and clinical features among patients.

Atypical chest pain: chest pain not caused by myocardial ischemia. CAD: coronary artery disease.

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