Regions of interest (ROIs) were manually drawn over the following organs: Liver, heart, kidney, quadriceps, bladder and adipose tissue. The ROIs were applied to the automatically co-registered PET images to measure the corresponding 18-FDG standard uptake value (SUV; mean and maximum). 18-FDG uptake was quantified using the following formula: SUV=tissue activity concentration (Bq/ml)/injected dose (Bq) × body weight (g).

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