The sample size was calculated using the GPOWER 3.1 program. By using a previous research finding, we assumed the mean CRP levels would be 4.9 ± 1.7 mg/lt in the non-dipper group and 3.8 ± 1.5 mg/lt in the dipper group. In order to show the differences between the two groups, the required sample size was calculated at 128, with 95% power and a two-sided type-1 error rate of 5%. We increased the sample size by 10% and aimed to reach 140 patients.11

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