Imprecision was assessed by the calculation of the optimal information size (OIS) [15], which is a conventional calculation to detect an SMD equal to the minimum clinically important difference and the post-SD of the control group. The calculation was performed using the comparison of the post-pre means in independent groups, based on the use of ANOVA of repeated measures (group-time interaction). Accepting an alpha risk of 0.05 and a beta risk of 0.1 (90% statistical power) in a two-sided contrast, the OIS would be 28 subjects in the experimental group and 28 in the control group to detect a standardized SMD effect size = 0.2.

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