InterPro and PRED-LIPO, a Hidden Markov Model, was used to classify the protein domain and lipoprotein signals, respectively [26,27]. Trans-membrane helixes were predicted by using the TMHMM server v.2.0 [28]. PSORTb was used for the prediction of prokaryotic localization sites [29]. Binding and active sites were predicted using COFACTOR and CASTp [30,31].

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