SPSS 16.0 (SPSS Inc., Chicago, IL, USA) was employed to analyze the results. Differences between two groups were compared with Student's t-test. Statistical comparisons were analyzed using one-way ANOVA followed by the Student-Newman-Keuls method. The difference of mice survival rate was detected by the Kaplan-Meier method followed by the log-rank test. The quantitative data were expressed as mean ± SD. p < 0.05 was considered to suggest a statistically significant difference.

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